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Updated: Jun 22, 2025

Comparing Metastatic Clear Cell Renal Cell Carcinoma Model Established in Mouse Kidney and on Chicken Chorioallantoic Membrane
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在清细胞细胞癌中,HIF-2α表达和代谢信号需要ACSS2

Zachary A Bacigalupa1,2,3, Emily N Arner1,2, Logan M Vlach1

  • 1Department of Medicine.

The Journal of clinical investigation
|June 28, 2024
PubMed
概括

抑制乙-A合成酶2 (ACSS2) 降低了缺氧诱导因子2-α (HIF-2α) 的水平,并抑制了清细胞细胞癌 (ccRCC) 的生长. 这一策略为在ccRCC治疗中向HIF-2α提供了一种新方法.

关键词:
癌症 癌症 癌症 癌症细胞生物学 细胞生物学氧气过低是因为缺氧.代谢过程中的代谢.分子生物学分子生物学

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