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对慢性病管理进展的图书统计和视觉分析
1Department of Nephrology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Medicine
|June 28, 2024
概括
这项研究分析了慢性病 (CKD) 研究史,确定了三个不同的进化阶段. 未来的CKD管理研究应该优先考虑开发模型和整合智能工具,以获得更好的患者结果.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 图书统计学 图书统计学
- 医学史 医学史 医学史
背景情况:
- 慢性病 (CKD) 是一个重大的全球卫生挑战,发病率高,社会负担高.
- 了解CKD研究的历史轨迹对于促进其识别,管理和降低患者和社会成本至关重要.
研究的目的:
- 系统地分析CKD管理研究的演变.
- 为临床医生提供关于CKD管理历史发展的基本理解.
主要方法:
- 从科学网络核心集合 (1948-2021) 中对26,133个CKD管理研究进行了图书统计分析.
- 使用VOS-viewer进行关键词同时出现的聚类和序列分析.
- 确定了研究主题,细分了出版阶段,并评估了动态进展.
主要成果:
- 慢性结核病研究经历了三个阶段:缓慢发展 (1948-1998),稳步增长 (1999-2010年) 专注于并发症和生活质量,以及快速发展 (2011-2022年) 具有7个重症管理集群.
- 研究之旅揭示了CKD管理演变的相互连接模型.
- 出版量和研究主题在确定阶段显示出不同的模式.
结论:
- 未来的CKD研究应该集中在建立稳健的管理模型上.
- 建议整合智能管理工具,以加强CKD护理.
- 这种历史分析可以作为未来研究扩展和改善CKD临床管理的参考.
相关概念视频
01:17Factors Affecting Renal Clearance: Renal Impairment
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Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
81
01:11Renal Failure: Dose Adjustments
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In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
79
01:07Determination of Renal Drug Clearance: Graphical and Midpoint Methods
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Renal clearance, a crucial parameter in pharmacokinetics, can be determined using two different methods: the graphical method and the midpoint method. These methods provide insights into the rate of drug excretion by the kidneys and aid in assessing renal function.
The graphical method involves plotting the rate of drug excretion in urine against the plasma drug concentration. By analyzing the graph, the clearance can be calculated and obtained. Drugs rapidly excreted by the kidneys exhibit a...
The graphical method involves plotting the rate of drug excretion in urine against the plasma drug concentration. By analyzing the graph, the clearance can be calculated and obtained. Drugs rapidly excreted by the kidneys exhibit a...
108
01:06Renal Drug Clearance: Overview
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Renal clearance is a crucial parameter in pharmacokinetics that quantifies the rate at which the kidneys excrete a drug. It represents a constant fraction of the central volume of distribution containing the drug that the kidney eliminates per unit of time.
Renal clearance can be calculated using different methods. One approach is to divide the urinary drug excretion rate by the plasma drug concentration. This method directly measures renal clearance, indicating the kidneys' efficiency in...
Renal clearance can be calculated using different methods. One approach is to divide the urinary drug excretion rate by the plasma drug concentration. This method directly measures renal clearance, indicating the kidneys' efficiency in...
181
01:27Dialysis
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Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
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01:08Renal Drug Clearance: Comparison Between Renal Excretion Methods
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Renal clearance is a critical parameter encompassing kidney filtration, secretion, and reabsorption processes. It is calculated using a specific equation to determine the rate at which the kidneys clear a drug.
Renal clearance is often associated with the renal glomerular filtration rate (GFR), which represents the rate at which plasma is filtered through the glomeruli in the kidney. When drug reabsorption is minimal and there is no active secretion, renal clearance is closely related to the...
Renal clearance is often associated with the renal glomerular filtration rate (GFR), which represents the rate at which plasma is filtered through the glomeruli in the kidney. When drug reabsorption is minimal and there is no active secretion, renal clearance is closely related to the...
120