抵抗训练对中年和老年人的炎症标志物的影响:元分析
Xinnian Cheng1, Zhiqiang Yang2
1Department of Arts and Sports, Jieyang Polytechnic , Jieyang 52200, Guagdong, China.
Archives of gerontology and geriatrics
|June 28, 2024
概括
耐力训练在老年人中显著降低了C-反应蛋白 (CRP),并显示了减少IL-6的潜力. 然而,它不会显著影响瘤亡因子-α (TNF-α) 水平.
科学领域:
- 老年学和运动科学
- 炎症和免疫学 炎症和免疫学
背景情况:
- 慢性炎症是衰老的标志,有助于与年龄有关的疾病.
- 支持炎症的细胞因子如CRP,IL-6和TNF-α是这种炎症的关键标志物.
- 抵抗训练是老年人广泛推的运动方式.
研究的目的:
- 系统地评估抵抗训练对中老年人和老年人的关键促炎细胞因子 (CRP,IL-6,TNF-α) 的影响.
- 综合当前关于抵抗运动在老年人群中调节炎症标志物的疗效的证据.
主要方法:
- 从主要电子数据库中检索到2022年3月的研究进行了全面的元分析.
- 纳入标准集中在老年人群中的抵抗运动干预和炎症标志物.
- 通过PEDro尺度评估研究质量,并使用RevMan 5.3.3分析数据.
主要成果:
- 分析包括了12项涉及388名参与者的研究.
- 抵抗训练显著降低了C反应蛋白 (CRP) 水平 (SMD = -0.56,P < 0.00001).
- 观察到减少IL-6的非显著趋势 (SMD = -0.25,P = 0.09),而TNF-α水平没有显著变化 (SMD = -0.07,P = 0.64).
结论:
- 抵抗训练在中年和老年人中有效降低CRP水平.
- 虽然阻力运动可能有助于降低IL-6,但它对TNF-α的影响并不显著.
- 特定的抵抗训练方案 (中等强度,每周3次,每周6-32周) 显示出降低老年人炎症标志物的潜力.
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