相关实验视频

Updated: Jun 22, 2025

Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation

Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation

Published on: October 31, 2019

珊瑚和其他Cnidaria通过定数灭来操纵微生物群

Benjamin Mason¹, David C Hayward², Aurelie Moya¹

¹ARC Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, QLD 4811, Australia.

Current biology : CB

|June 28, 2024

概括

珊瑚有一个独特的基因,AmNtNH1,它会使细菌的定量级信号分子失活. 这一发现揭示了一个新的珊瑚免疫机制,涉及从细菌转移基因,帮助微生物调节.

科学领域:

海洋生物学海洋生物学
免疫学免疫学免疫学
微生物生态学微生物生态学

背景情况:

珊瑚粘液拥有动态的微生物群,对沉积物清除和防御等功能至关重要.
抗微生物 (AMP) 是已知的珊瑚微生物组的调节者,通常是微生物起源的.
单核生物可以通过干扰细菌的定数信号来操纵微生物组.

研究的目的:

研究珊瑚免疫力和微生物群调节机制.
为了确定参与珊瑚-宿主-微生物相互作用的新基因.
探索与细菌通信相关的珊瑚基因的起源和功能.

主要方法:

研究了珊瑚礁建造者珊瑚Acropora millepora的免疫力.
鉴定和表征了珊瑚基因AmNtNH1.1.
分析了Scleractinia和其他类动物中相关蛋白质的分布.
检查了在免疫挑战和幼虫定居期间的表达时的基因诱导.

主要成果:

发现了珊瑚基因AmNtNH1,能够使细菌的定数信号分子 - - 乙类荷马塞林乳 (AHLs) - - 失活.
在成年珊瑚中,AmNtNH1在免疫挑战时被诱导,并在幼虫定居期间表达.
在Scleractinia和其他类动物中发现了密切相关的蛋白质,细菌的亲属表明横向基因转移.
这代表了以前在Metazoa中未知的微生物组操纵机制.

结论:

珊瑚利用一种细菌起源的基因 (AmNtNH1) 来干扰细菌的定数信号,代表了一种新的免疫策略.
这种机制使得珊瑚可以操纵它们的微生物群,可能是通过破坏细菌交流.
这些发现表明,从细菌向鱼的横向基因转移提供了新的免疫能力.
这种部署细菌基因以进行细菌间竞争的策略在Metazoa中可能很普遍.

关键词:

昆虫类动物 (Cnidaria) 是一个类动物.这是一种NtN-酶.亚基尔荷马塞林乳乳珊瑚的微生物群侧向基因转移是横向的议员数量限制的灭.这种共生是共生.

更多相关视频

Author Spotlight: Advancing Coral Culture - Creating a Semi-Quantitatively Controlled Microenvironment System to Counter Current Limitations

Author Spotlight: Advancing Coral Culture - Creating a Semi-Quantitatively Controlled Microenvironment System to Counter Current Limitations

Published on: July 21, 2023

Inducing Polyp Bail-out in Coral Colonies to Obtain Individualized Micropropagates for Laboratory Experimental Use

Inducing Polyp Bail-out in Coral Colonies to Obtain Individualized Micropropagates for Laboratory Experimental Use

Published on: April 28, 2022

相关概念视频

Bacterial Signaling

Bacterial Signaling

Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...

Bioremediation

Bioremediation

Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.