心声学衍生的向前左心室输出改善了对静脉心力衰竭的风险预测
Francesco Gentile1, Paolo Sciarrone2, Giorgia Panichella1
1Health Science Interdisciplinary Center, Scuola Superiore Sant'Anna, Pisa, Italy.
概括
前左心室 (LV) 输出量,如LV外流通道速度-时间积分和中风体积指数,比射出分数更好地预测心力衰竭 (HF) 死亡率. 这些血液动力学标志物改善了HF患者的风险分层.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏衰竭研究研究
背景情况:
- 左心室喷射分数 (LVEF) 是心力衰竭 (HF) 的标准但有争议的预后标志物.
- 前左心室 (LV) 输出的心声测量可以为风险预测提供卓越的血液动力学表示.
研究的目的:
- 评估心声回声前置LV输出指标是否可以改善心肌缩功能障碍的HF患者的风险预测.
- 为了比较 LV 期货输出指标与 LVEF 的预测值.
主要方法:
- 分析了1509名稳定的HF患者的LVEF<50%在最佳治疗中.
- 对LV输出管道速度时间积分 (VTI),中风体积指数 (SVi) 和心脏指数的回声心脏学评估.
- 对心脏病和所有死因的随访时间均为28个月.
主要成果:
- 预期的LV输出指标 (LVOT VTI,SVi,心脏指数) 显著预测死亡率 (P < .001),而不是LVEF (P > .05).
- 确定了最佳的截止点:LVOT VTI 15 cm,SVi 38 mL/m2,心脏指数 2 L/min/m2.
- 将这些措施纳入风险模型显著改善了预测 (P < .001).
结论:
- 声心图前置LV输出评估提高了跨多种LVEF的HF患者的风险预测.
- 这些血液动力学测量超越了传统的临床,生物幽默和心声学预后标记.
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