[在转移玻璃化胚胎囊后的临床结果与冷指示相关]
Emmanuelle Bodin1, Romane Sainte-Rose1, Claire Petit1
1Service de médecine et biologie de la reproduction, hôpital Bretonneau, 37044 Tours, France.
Gynecologie, obstetrique, fertilite & senologie
|June 28, 2024
概括
胚胎冷的适用性在冷胚胎转移 (FBT) 后不会显著影响活产率. 患者的年龄仍然是一个关键因素,但冷原因在辅助生殖技术中的影响力似乎较小.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 胚胎学 胚胎学
- 不孕症研究 不孕症研究
背景情况:
- 冷胚胎细胞移植 (FBT) 在法国的辅助生殖技术 (ART) 周期中占有越来越多的比例.
- 了解影响FBT成功的因素对于优化患者的治疗结果至关重要.
研究的目的:
- 根据胚胎冷的主要指示,比较FBT后的活产率.
- 确定结原因是否影响FBT成功率.
主要方法:
- 在2020年1月至2022年6月期间,对963个FBT周期进行了回顾性分析.
- 在三个主要的结迹象中比较活产率:卵巢过度刺激 (OHS),在怀孕 (第二次请求) 后的新鲜胚胎细胞移植 (BT) 和BT衰竭.
- 采用了单变量和多变量分析,并对患者年龄等混因素进行了调整.
主要成果:
- 在所有FBT周期中,观察到总体活产率为28%.
- 与OHS组相比,BT衰竭组的活产率明显较低.
- 在调整了混因素后,患者年龄仍然是活产的重要预测因素,而冷的指示则没有.
结论:
- 在考虑混因素时,胚胎冷的适用性似乎不会显著影响冷芽细胞移植结果.
- 需要进一步的多中心前性研究来验证这些发现并提供更明确的结论.
相关概念视频
In Vitro Fertilization
239
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
239
Meiosis II
183.3K
Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each...
183.3K


