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Updated: Jun 22, 2025

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

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马赛克染色体改变对精神分裂症的贡献

Kaihui Chang1, Xuemin Jian2, Chuanhong Wu3

  • 1The Affiliated Hospital of Qingdao University & The Biomedical Sciences Institute of Qingdao University (Qingdao Branch of SJTU Bio-X Institutes), Qingdao University, Qingdao, China; School of Basic Medicine, Qingdao University, Qingdao, China; National Engineering Research Center of Innovation and Application of Minimally Invasive Instruments, Sir Run-Run Shaw Hospital, Zhejiang University, Hangzhou, China.

Biological psychiatry
|June 28, 2024
PubMed
概括

马赛克染色体变异或体质复制数变异 (sCNVs) 在精神分裂症 (SCZ) 患者中明显更常见. 这些早期发育变异在SCZ遗传风险中起着关键作用.

关键词:
10q21.11.1 这里是10q21.112q21.31-21.32 的时间.副本数量的变化 副本数量的变化马赛主义 (Mosaicism) 是一个教派.精神分裂症是一种精神分裂症.身体上的损失 身体上的损失

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