结合性组织疾病中临床相关的生物标志物与结合性组织疾病相关的间歇性肺部疾病
Janelle Vu Pugashetti1, Dinesh Khanna2, Ella A Kazerooni3
1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan.
Rheumatic diseases clinics of North America
|June 28, 2024
概括
鉴定生物标志物对于诊断和预测患有间歇性肺病 (ILD) 并发症结合组织疾病 (CTD) 患者的结果至关重要. 本综述强调了CTD-ILD管理生物标志物的近期进展.
科学领域:
- 肺部病理学 肺部病理学
- 类风湿病学 类风湿病学
- 生物标志物发现发现
背景情况:
- 间歇性肺病 (ILD) 是连接组织疾病 (CTD) 患者死亡的重要原因.
- 早期诊断和CTD-ILD的管理对于改善患者的治疗结果至关重要.
- 现有的CTD-ILD诊断和预后工具需要改进.
研究的目的:
- 审查诊断CTD-ILD的临床相关生物标志物.
- 为突出CTD-ILD的预后生物标志物的最新进展.
- 为CTD-ILD提供诊断和预后生物标志物策略的概述.
主要方法:
- 对CTD-ILD中的生物标志物研究的文献综述.
- 包括最近的原子研究.
- 专注于临床相关的诊断和预后生物标志物.
主要成果:
- 生物标志物对于在CTD患者中早期识别ILD至关重要.
- 放射性和基于血液的生物标志物是已知的工具.
- -OMIC研究正在确定新的预后生物标志物.
结论:
- 生物标志物研究的进步为CTD-ILD提供了更好的诊断能力.
- 新型生物标志物在预测疾病进展和结果方面表现有前途.
- 综合生物标志物方法是优化CTD-ILD患者护理的关键.
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