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基于SEER的分析,分析了与HPV相关的口腔膜状细胞癌的趋势

Su Il Kim¹, Jung Woo Lee², Young-Gyu Eun³

¹Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University School of Medicine, Kyung Hee University Hospital at Gangdong, #892 Dongnamro, Gangdong-gu, Seoul, 05278, Korea.

Infectious agents and cancer

|June 29, 2024

概括

人类乳头瘤病毒 (HPV) 阳性口腔状细胞癌 (OPSCC) 病例的比例正在增加,预计将继续上升. 趋势因人口因素而异,需要针对HPV相关的OPSCC制定有针对性的预防策略.

科学领域:

在瘤学瘤学.
流行病学流行病学
公共卫生公共卫生

背景情况:

之前的研究缺乏对HPV相关的口腔状细胞癌 (OPSCC) 在各种因素中的比例趋势的详细分析.
了解这些趋势对于公共卫生倡议和患者管理至关重要.

研究的目的:

评估美国HPV相关OPSCC的比例趋势.
分析这些趋势如何因人口因素而有所不同.
预测HPV阳性和HPV阴性OPSCC的未来趋势.

主要方法:

使用监测,流行病学和最终结果 (SEER) 数据库 (2010-2017) 的回顾性队列研究.
包括13,081名被诊断为OPSCC的患者在舌头底部,后壁,软 palatus和桃体.
分析了人口因素,并使用自回归集成移动平均 (ARIMA) 模型进行趋势预测.

主要成果:

接受HPV检测的患者比例每年增加,到2014年超过50%.
在OPSCC中,HPV阳性率从2010年的66.37%增加到2016年的79.32%.
在桃体或舌头底部OPSCC中,与后壁或软相比,HPV阳性显著更高.

结论:

阳性OPSCC病例的比例已经增加,预计将继续上升.
在HPV阳性和HPV阴性OPSCC趋势中存在显著的人口差异.
这些发现为制定与HPV相关的OPSCC有针对性的预防措施提供了基础.

关键词:

流行病学流行病学在HPV病毒状态下.口腔膜状细胞癌的癌症.在 SEER 数据库中,我们可以看到自动回归集成移动平均线 (ARIMA) 模型.

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