在COVID-19缓解措施期间早产儿的特征
Yizhen Amy Liu1,2, Alexia Matheson2, Rochelle Sleaby2
1Department of Obstetrics and Gynaecology, Monash University, Melbourne, Victoria, Australia.
概括
通过减少自发性早产 (sPTL) 而没有早产前膜破裂 (PPROM),COVID-19缓解措施可能减少了早产. 这种转变可能导致怀孕后期PPROM病例的增加.
科学领域:
- 产科和妇科 产科和妇科
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 随着COVID-19大流行,全球范围内实施了缓解措施.
- 这一时期的一个值得注意的观察是早产率的降低.
- 这种关联引起了科学界对了解潜在原因的重大兴趣.
研究的目的:
- 调查流行病缓解期间观察到早产率下降的原因.
- 在缓解措施之前和期间探索早产分娩队伍的特定特征.
主要方法:
- 进行了一项回顾性队列研究,比较了两组早产妇女.
- 暴露队列是在缓解措施期间构思的 (2019年11月至2020年2月),而非暴露队列是在此之前构思的 (2019年11月至2018年2月).
- 对比了母亲的特征,怀孕并发症,产前和产后护理以及分娩指示.
主要成果:
- 缓解措施暴露的队列 (8.1%) 的早产率略低于未暴露的队列 (9.4%).
- 没有早产前膜破裂 (PPROM) 的自发早产 (sPTL) 在暴露组显著减少 (13.1%vs24.2%).
- 相反,暴露队列中的PPROM率增加 (48.0%与35.6%相比),PPROM后的自发分娩率更高 (40.1%与24.1%相比).
结论:
- 在疫情缓解期间早产率的减少似乎与没有PPROM的sPTL下降有关.
- 劳动模式的这种变化可能导致怀孕后期PPROM的发病率增加.
- 需要进一步的研究,以充分阐明缓解措施和早产子类型之间的复杂关系.
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