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Updated: Jun 22, 2025

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[原始编辑方法和RNA设计程序]

E V Mikhaylova1,2, B R Kuluev1, G A Gerashchenkov1

  • 1Institute of Biochemistry and Genetics, Ufa Federal Research Center, Russian Academy of Science, Ufa, 450054 Russia.

Molekuliarnaia biologiia
|June 29, 2024
PubMed
概括

主编辑是一种革命性的CRISPR/Cas基因组编辑技术,可以在没有捐赠DNA的情况下精确修改DNA. 进一步的开发旨在提高其效率,以便在农业,工业和医学领域得到更广泛的应用.

关键词:
克里斯普尔是什么意思?克里斯普尔是什么意思?这就是PE PE PE.计算机程序 计算机程序导向RNA指导RNA是指导RNA的指导RNA.nCas9 的使用情况.ngRNARNA 是一个尼克尼克尼克尼克尼克是什么意思在线工具在线工具.RNA pegRNA 是一个主编辑主要编辑.

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RNA editing is a post-transcriptional modification where a precursor mRNA (pre-mRNA) nucleotide sequence is changed by base insertion, deletion, or modification. The extent of RNA editing varies from a few hundred bases, in mitochondrial DNA of trypanosomes, to a just single base, in nuclear genes of mammals. Even a single base change in the pre-mRNA can convert a codon for one amino acid into the codon for another amino acid or a stop codon. This type of re-coding can significantly affect the...
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