语音假肢和喉切除术后的口腔微生物群之间的细菌殖民概况的一致性:一项实验研究
Salvatore Cocuzza1, Antonino Maniaci2, Ignazio La Mantia1
1Department of Medical, Surgical Sciences and Advanced Technologies "GF Ingrassia" ENT Section, University of Catania, Via S. Sofia 87, 95123 Catania, Italy.
Auris, nasus, larynx
|June 29, 2024
概括
在喉切除术患者的语音假体的微生物殖民与口腔微生物群有关. 了解这些模式可以改善语音假体护理和患者的生活质量.
科学领域:
- 微生物学 微生物学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 医疗器械 医疗器械
背景情况:
- 语音假肢 (VP) 的微生物殖民是喉腔切除患者的一个重大问题,影响了他们的生活质量 (QoL).
- 口腔微生物模式和VP性能之间的关系需要进一步调查,以优化患者护理.
研究的目的:
- 探索口腔微生物模式,人口因素和喉切除个体的语音假体性能之间的相关性.
- 确定与VP殖民相关的特定微生物物种及其对患者报告结果的影响.
主要方法:
- 分析了30名喉切除术患者的VPs和口腔中的微生物殖民.
- 收集了人口统计数据,包括年龄,质子抑制剂 (PPI) 使用和酒精消费.
- 微生物分析包括细菌和真菌物种的识别,并评估VP和口腔微生物群的一致性.
主要成果:
- 在语音假体和口腔微生物群之间观察到显著的一致性 (kappa=0.315,p < 0.004).
- 虽然细菌殖民并没有显著影响与语音相关的QoL得分 (VHI,VrQoL,SF-36),但真菌殖民显示出了显著的影响.
- 与Candida albicans相比,Candida krusei的殖民与更好的主观语音结果 (VHI,VrQoL,SF-36) 有关.
结论:
- 在喉腔切除患者的口腔微生物群和语音假体殖民之间存在显著的相关性.
- 菌殖民模式,特别是Candida krusei,似乎对语音假体的性能和患者的语音质量产生积极影响.
- 这些发现表明,针对口腔和VP微生物群的有针对性的策略可以增强对喉切除患者的护理.
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