患有后COVID综合征的成年人的认知表现:来自德国病例控制研究的结果
Andrea E Zülke1, Melanie Luppa1, Kerstin Wirkner2
1Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, 04103, Leipzig, Germany.
Journal of psychiatric research
|June 29, 2024
概括
与健康个体相比,患有后COVID综合征 (PCS) 的成年人表现出情节性记忆和视觉空间能力的认知缺陷. 压力和疲劳也会影响PCS患者的认知表现.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 传染性疾病 传染性疾病
背景情况:
- 后COVID综合征 (PCS) 经常与认知障碍有关.
- 以前的研究经常使用小样本,并没有考虑相关的共变量.
研究的目的:
- 评估PCS的成年人,没有PCS的SARS-CoV-2幸存者和健康对照者的认知表现.
- 研究社会人口统计学,心理健康和疲劳与PCS认知表现和主观认知衰退 (SCD) 的关联.
主要方法:
- 使用多变量回归分析来比较认知表现并评估共变量关联.
- 来自德国莱比锡LIFE长期COVID研究的数据包括561名成年人.
主要成果:
- 患有PCS的成年人 (n=410) 与健康对照人 (n=64) 相比,表现出更差的情节性记忆和视觉空间能力.
- 在执行功能,口语流或全球认知方面没有发现显著的认知障碍.
- 既没有PCS,也没有PCS之前的SARS-CoV-2感染与SCD的更高几率有关.
- 高龄,压力和疲劳与特定认知领域的表现较差相关.
结论:
- 情节性记忆和视觉空间能力的认知缺陷在后COVID综合征中很普遍.
- 对这些领域的常规认知查可能有助于识别有风险的个体.
- 年龄,压力和疲劳等因素显著影响PCS的认知结果.
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