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Updated: Jul 22, 2026

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在小鼠模型中,重复暴露于会通过PINK1/PARKIN介导的线粒体功能障碍导致病的严重程度

Sneha Kumari1, Payal Singh1, Rashmi Singh1

  • 1Department of Zoology, MMV, Banaras Hindu University, Varanasi 221005, India.

Cellular signalling
|June 29, 2024
PubMed
概括

这项研究表明,在小鼠中,重复暴露于二氧化会导致渐进性肺纤维化,其特征是细胞外基质沉积和线粒体功能障碍. 减少的自和髓标志物表明纤维化在35天内恶化.

关键词:
线粒细胞衰变 (mitophagy) 是一种氧化应激是一种氧化应激.肺部纤维化 肺部纤维化化是一种化.

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