了解北印度肺外结核病的变化模式
Lipika Singhal1, Parakriti Gupta1, Noorul Aysha K1
1Department of Microbiology, GMCH-32, Chandigarh, India.
Indian journal of medical microbiology
|June 29, 2024
概括
印度的肺外结核病例在四年内呈现下降趋势,而肺部结核病最常见. 在EPTB病例中,有7.45%的患者出现了抗利芬素耐药性,这凸显了加强控制计划的必要性.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 结核病 (TB) 构成了全球重大健康负担,印度占据了大量病例.
- 肺外结核 (EPTB) 占结核病例的相当一部分,特别是在HIV阳性个体中.
- 印度对EPTB趋势的研究有限,需要进行本地研究.
研究的目的:
- 在印度的一家三级保健中心调查肺外结核病 (EPTB) 的趋势和特征.
- 分析EPTB的发病率,常见表现和药物耐药性模式,在一定的时间内.
主要方法:
- 一项回顾性研究分析了10560个样本,持续了4年3个月.
- 通过临床怀疑,微生物学证据和基于盒子的核酸放大测试 (CBNAAT) 证实了EPTB的诊断.
主要成果:
- 18%的肺外样本对EPTB呈阳性.
- 排骨结核病是最常见的表现 (31%),其次是淋巴腺炎.
- 在7.45%的阳性EPTB样本中检测到里芬辛耐药性,在淋巴结吸附中更高的率.
结论:
- 观察到EPTB阳性的下降趋势,尽管在2022年出现了上升.
- 年轻的成年人受到影响最大,肺结核是占主导地位的形式.
- 该研究强调,由于观察到耐药性,需要加强结核病控制计划.
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