在亚急性和慢性肺栓塞患者的左心室相位功能障碍不同程度的阻塞:一个MRI特征跟踪研究研究
Meng-Ting Shen1, Yuan Li1, Li-Ting Shen1
1Department of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Journal of magnetic resonance imaging : JMRI
|June 30, 2024
概括
在肺栓塞 (PE) 患者中,左心房 (LA) 功能受损,亚急性和慢性病例之间没有显著差异. 右心室 (RV) 直径是监测PE中LA功能障碍的关键指标.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 肺部医学 肺部医学
背景情况:
- 在亚急性和慢性肺栓塞 (PE) 中,左心房 (LA) 阶段功能变化尚不清楚.
- 调查这些变化对于理解PE病理生理学和患者结果至关重要.
研究的目的:
- 用MRI特征追踪 (MRI-FT) 评估亚急性和慢性PE患者的LA相位应变和LA-右心室 (RV) 相互作用.
- 评估不同程度的阻塞对PE患者的LA功能的影响.
主要方法:
- 追溯分析了103名PE患者 (54名亚急性,49名慢性) 和80名使用3.0TMRI的对照组.
- 使用MRI特征跟踪 (MRI-FT) 来测量LA储,管道和活性的纵向应变 (εs, εe, εa) 和应变率 (SRs, SRe, SRa).
- 统计分析包括ANOVA,t测试,曼-惠特尼U测试和线性回归来确定相关性和关联.
主要成果:
- 与对照组相比,亚急性和慢性PE患者表现出明显减少的LA菌株和菌株率.
- 在亚急性和慢性PE组之间没有观察到LA菌株的显著差异.
- 严重的PE亚组比轻度和中度的亚组显示出更高的LA活性应变 (εa) 和应变率 (SRa).
- 拉氏菌株与RV直径和双心室菌株有显著的相关性,而RV直径与拉氏菌株独立相关.
结论:
- 核磁共振-FT显示在亚急性和慢性PE患者中,LA阶段功能显著受损.
- RV直径被确定为PE中LA功能障碍的独立预测指标和潜在监测指标.
- 在严重的PE中,LA活跃功能似乎升高,这表明存在补偿机制.
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