营养保健品在乳病中的潜力
Mahtab Jahdkaran1,2, Nastaran Asri3, Hadi Esmaily1
1Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
营养药物有望通过向炎症和肠道健康来管理腹腔疾病 (CD). 需要进一步的研究来了解它们的全部治疗潜力,而不仅仅是无质饮食 (GFD).
科学领域:
- 胃肠病学和营养科学 胃肠病学和营养科学
- 免疫学 免疫学 免疫学
- 药理学 药理学是指药理学的学科.
背景情况:
- 乳病 (CD) 是一种普遍存在的,由摄入质引发的遗传性炎症状况.
- 目前的管理依赖于严格的无质饮食 (GFD),这提出了重大的坚持挑战.
- 营养药,来自食物来源的生物活性化合物,为CD提供了潜在的治疗途径.
研究的目的:
- 审查各种营养保健品在治疗乳病 (CD) 的潜力.
- 探索营养药物如何调节关键的CD相关途径.
- 突出需要进一步研究CD.的营养学机制.
主要方法:
- 关于营养药和腹腔疾病的研究的综合文献综述.
- 营养品的分析,包括植物化学品,脂肪酸,维生素,矿物质,酶和氨基酸.
- 对营养药对CD特异性分子和细胞通路的影响的评估.
主要成果:
- 营养药可以调节谷蛋白消化,肠道屏障完整性和组织转谷氨酶 (TG2) 活性.
- 潜在的益处包括调节免疫反应,炎症,氧化应激和肠道微生物群组成.
- 各种营养药类表明能够影响CD病变的发生.
结论:
- 营养药物是一种有前途的辅助方法,用于治疗腹腔疾病.
- 对细胞和分子机制的进一步研究对于治疗开发至关重要.
- 有针对性的研究可以推进超越饮食限制的乳病的新型干预措施.
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