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Updated: Jun 22, 2025

Malachite Green Assay for the Discovery of Heat-Shock Protein 90 Inhibitors
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选择性化Hsp90作为一种代谢开关,促进瘤细胞增殖

Isabelle E Logan1, Kyle T Nguyen2, Tilottama Chatterjee2

  • 1Department of Biochemistry and Biophysics, College of Science, Oregon State University, Corvallis, OR, 97331, USA; Center for Translational Science, Florida International University, Florida, 34987, USA.

Redox biology
|June 30, 2024
PubMed
概括

氨酸化,瘤中的一个过程,激活热冲击蛋白90 (Hsp90) 驱动瘤细胞生长. 化Hsp90充当代谢开关,为NF2相关的 Schwannomatosis 提供新的治疗点.

关键词:
细胞代谢 细胞代谢在Hsp90中,它是Hsp90的.神经纤维细胞增生症这是一个P2X7受体.瘤是一个瘤.氨酸化为铁素.

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