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低剂量的二甲基酸盐通过M2巨细胞的极化和阻断氧化应激减弱了小鼠的结肠炎相关癌症

Ismahane Abdelaziz1, Abdelkader Bounaama1, Bahia Djerdjouri1

  • 1Tamayouz_Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, University of Sciences and Technology Houari Boumediene (USTHB), Algiers, Algeria.

Toxicology and applied pharmacology
|June 30, 2024
PubMed
概括

低剂量的二甲基酸盐 (DMF) 通过减少炎症和氧化应激,显示出作为治疗大肠炎相关癌症 (CAC) 的化疗剂的前景. 然而,高剂量的DMF加剧了CAC,突出了双重效应,需要仔细考虑剂量才能有效治疗.

关键词:
大肠炎相关的癌症甲基烟酸二甲基二甲基烟酸二甲基烟酸二甲基烟酸二甲基烟酸二甲基烟酸二甲基烟酸二甲基烟酸二甲基烟酸巨细胞的两极分化这就是NRF2的NRF2.氧化应激是一种氧化应激.在 p53 里,p53 是一个 p53 的类型.

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