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相关概念视频

Bone Disorders01:29

Bone Disorders

3.5K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.5K
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

3.9K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
3.9K
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

2.9K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
2.9K

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相关实验视频

Updated: Jun 22, 2025

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

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五个东南亚国家的骨周转标记参考数据库.

Joon Kiong Lee1, Hui Min Khor2, Pojchong Chotiyarnwong3

  • 1Department of Orthopedic Surgery, Beacon Hospital, Petaling Jaya, Selangor, Malaysia.

Bone
|June 30, 2024
PubMed
概括
此摘要是机器生成的。

这项研究确定了东南亚绝经前妇女骨循环标记 (BTM) 的第一个参考范围. 这些发现对于该地区精确的骨质疏松症评估和管理至关重要.

关键词:
骨头翻转标记器标记器骨质疏松症是一种骨质疏松症.东南亚的东南亚地区.女人 女人 女人 女人 女人

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相关实验视频

Last Updated: Jun 22, 2025

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

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Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
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Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation

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Protocol for Developing a Femur Osteotomy Model in Wistar Albino Rats
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科学领域:

  • 内分泌学 在内分泌学.
  • 骨的新陈代谢 骨的新陈代谢
  • 人口健康 人口健康

背景情况:

  • 骨质疏松症的患病率很高,特别是在发展中国家.
  • 亚洲人群缺乏已确立的骨周转标记 (BTM) 参考范围.
  • 准确的BTM对于骨质疏松症的诊断和监测至关重要.

研究的目的:

  • 为五个东盟国家开发一个区域BTM参考数据库.
  • 为了确定血清Procollagen 1 N-终端 Propeptide (P1NP),骨素 (OC) 和Beta-Crosslaps (CTX) 的参考间隔.
  • 为东南亚骨质疏松症管理提供基础.

主要方法:

  • 来自马来西亚,菲律宾,新加坡,泰国和越南的综合国家具体数据.
  • 分析了746名年龄在20-44岁之间的健康的绝经前妇女.
  • 使用自动化免疫检测系统测量P1NP,OC和CTX.

主要成果:

  • 已建立的参考间隔:CTX (128-811 ng/L),OC (9.0-33.0 μg/L),P1NP (22.8-96.5 μg/L). 它们可以分为两种.
  • 不包括20岁以下的人:CTX (117-678 ng/L),P1NP (21.6-85.8 μg/L),OC (3.5-27.0 μg/L).
  • 观察到国家间的变化和30岁以后随着年龄的增长而减少的BTM.

结论:

  • 这项研究为健康的绝经前东南亚妇女提供了第一个BTM参考间隔.
  • 这些间隔对于准确评估该地区的骨周转率至关重要.
  • 有助于改善骨质疏松症评估和患者监测.