门性高血压的脑部方面:肝脏脑病
Karen Louise Thomsen1, Michael Sørensen2, Kristoffer Kjærgaard1
1Department of Hepatology and Gastroenterology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, Aarhus N 8200, Denmark.
Clinics in liver disease
|June 30, 2024
概括
肝脑病 (HE) 是门高血压的脑部并发症,导致人格变化和注意力缺陷. 治疗包括乳糖和利法西明,但HE表明晚期肝病.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 神经学 神经学
- 胃肠病学 胃肠病学
背景情况:
- 门高血压导致大脑并发症,主要是肝脏脑病变 (HE).
- HE是一种严重的脑功能障碍,与肝功能衰竭和移植系统位有关.
- 病原发生包括高氨血和全身炎症,表现为人格变化和注意力减少.
研究的目的:
- 概述肝脏脑病变的原因,病原和临床谱.
- 描述急性发作和复发性急性发作当前的治疗策略.
- 强调HE在晚期肝病的预后影响.
主要方法:
- 关于门高血压和肝脏脑病的文献综述.
- 对高血压病原,临床表现和分级系统的分析.
- 评估治疗干预措施,包括乳糖和rifaximin.
主要成果:
- 他出现了微小到严重的神经缺陷 (第四级昏迷).
- 情节通常是偶发的和反复的.
- 乳糖是主要的治疗方法;对于复发病例,添加利法西明.
结论:
- 预发性事件的早期治疗和特定的抗HE疗法至关重要.
- 虽然治疗对预防有效,但HE意味着晚期肝病.
- 高血压的出现与预后不佳有关.
更多相关视频
相关概念视频
Hepatic Portal System
1.2K
The hepatic portal system, a critical part of our circulatory framework, transports nutrient-laden, deoxygenated blood from the gastrointestinal tract and spleen to the liver. This ingenious system plays an indispensable role in maintaining our body's metabolic equilibrium.
At its core, the hepatic portal vein is the result of a confluence of the superior and inferior mesenteric veins along with the splenic vein. Each of these veins has a unique role. The superior mesenteric vein is...
At its core, the hepatic portal vein is the result of a confluence of the superior and inferior mesenteric veins along with the splenic vein. Each of these veins has a unique role. The superior mesenteric vein is...
1.2K
Esophageal Varices-I: Introduction
105
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
105
Esophageal Varices-II: Clinical Features and Management
57
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
57
Cerebral Hemispheres
321
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
321
Arteries of the Head and Neck
1.2K
The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
1.2K
Liver Histology
705
The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
Hepatocytes perform a variety of essential functions. They secrete...
705


