怀孕期间C型肝炎感染的流行病学:西弗吉尼亚州的模式和趋势,使用全州监测数据
Amna Umer1, Candice Lefeber1, Christa Lilly2
1Department of Pediatrics, School of Medicine, West Virginia University, Morgantown, WV, USA.
Journal of addictive diseases
|July 1, 2024
概括
在怀孕期间感染C型肝炎病毒 (HCV) 与使用物质有关. 吸烟或使用阿片类药物/兴奋剂的孕妇在西弗吉尼亚州的HCV风险最高.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 药物使用流行病导致C型肝炎病毒 (HCV) 感染的增加.
- 有限的数据存在于怀孕人口中HCV的当前患病率.
研究的目的:
- 为了确定西弗吉尼亚州 (WV) 母亲HCV感染的患病率.
- 为了确定与WV的母体HCV感染相关的因素.
主要方法:
- 一项基于人口的回顾性队列研究分析了在2020年1月1日至2024年1月30日期间在WV分娩的孕妇.
- 对于HCV风险因素,逻辑-二项式回归模型估计了调整后风险比率 (ARR) 和95%置信区间 (CI).
主要成果:
- 孕产妇的HCV感染率为每1000例分娩中的38例.
- 与农村相比,白人,教育程度较低的人,医疗补助 (Medicaid) 接受者以及城市/郊区的人群中,HCV风险更高.
- 使用阿片类药物 (ARR 4.43) 和使用兴奋剂 (ARR 1.79) 显示了最高的相关风险,其次是吸烟 (ARR 3.51).
结论:
- 母亲的年龄,种族,教育和保险类型与HCV感染有关.
- 在怀孕期间吸烟和使用阿片类药物/兴奋剂显著增加西弗吉尼亚州的HCV风险.
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