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Updated: Jun 22, 2025

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
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Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods

Published on: July 17, 2019

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洞察细胞信号机制中全长CRaf激酶的分子基础和动态

Van A Ngo1

  • 1Advanced Computing for Life Sciences and Engineering, Science Engagement Section, Computing and Computational Sciences, National Center for Computational Sciences, Oak Ridge National Laboratory, Oak Ridge, Tennessee.

Biophysical journal
|July 1, 2024
PubMed
概括

这项研究使用人工智能和模拟提出了CRaf激酶的第一个全长结构模型,揭示了其动态性质和相互作用. 这促进了对细胞信号通路和药物机制的理解.

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