加速度计确定体力活动和久坐行为与中年妇女的肠道微生物组的关联:一种组成数据方法
Inmaculada Pérez-Prieto1,2, Jairo H Migueles3, Nerea M Molina1,2
1Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Granada, Spain.
Scandinavian journal of medicine & science in sports
|July 1, 2024
概括
客观的体力活动评估显示,中度至强度的体力活动 (MVPA) 可能会增加有益的肠道细菌. 这项研究强调了特定的运动行为,而不仅仅是整体活动,如何影响肠道微生物组合.
科学领域:
- 微生物组研究的研究.
- 人类生理学 人类生理学
- 在健康领域的数据科学.
背景情况:
- 身体活动 (PA) 有益于肠道微生物群,但由于主观PA评估,研究结果各不相同.
- 客观的PA测量减少了误差,并允许评估久坐行为 (SB).
- 组合数据分析 (CDA) 解释了运动行为中的相互依赖性.
研究的目的:
- 调查加速仪评估行为 (SB,LPA,MVPA) 与肠道微生物组之间的关联.
- 利用CDA分析运动行为及其对肠道微生物组成的影响.
- 为了识别受不同程度的身体活动和久坐时间影响的特定肠道细菌.
主要方法:
- 对来自1966年芬兰北方出生队列的289名妇女进行横截面研究.
- 在使用手腕加速度计进行14天的客观PA评估.
- 对肠道微生物组和运动行为数据应用的组合数据分析.
主要成果:
- 在MVPA-SB组之间,微生物α和β多样性没有显著差异.
- CDA显示,运动行为与微生物α-多样性之间没有显著的关联.
- 将时间从LPA或SB重新分配到MVPA显著增加了生产丁酸盐的细菌 (Agathobacter,Lachnospiraceae CAG56) 的丰度.
结论:
- 身体活动和久坐不动行为与整体肠道微生物多样性无关.
- 中度至强度的体力活动 (MVPA) 与特定短链脂肪酸产生的肠道微生物的丰富性增加有关.
- 客观测量和CDA揭示了运动行为和肠道细菌组成之间的特定联系.
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