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Updated: Jun 22, 2025

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在Caenorhabditis elegans中的瘤性Ras变异活性中的功能区别

Haimeng Lyu1, Helen M Chamberlin1

  • 1Department of Molecular Genetics, Ohio State University, 484 West 12th Avenue, Columbus, OH 43210, USA.

Disease models & mechanisms
|July 1, 2024
PubMed
概括

在癌症中至关重要的瘤性Ras变体在细胞网络中表现出不同的行为. 这项研究揭示了不同Ras突变如何在体内影响发育和药物反应.

关键词:
在C. elegans vulva的发育过程中.致癌的Ras变种可能会导致癌症.在 Ras/MEK 信号通道上.

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