描述和评估带有或没有前性痴呆症的肌缩性侧面硬化症的行为症状:一个范围审查
Ana Paula Trucco1, Tamara Backhouse, Eneida Mioshi
1School of Health Sciences, University of East Anglia, Norwich, Norfolk, UK.
Current opinion in neurology
|July 1, 2024
概括
行为症状在肌缩性侧面硬化症 (ALS) 和带前性痴呆症 (ALSFTD) 的ALS中很常见,影响患者的护理. 本次审查强调了这些症状的广泛性以及需要更好的临床评估和管理策略.
科学领域:
- 神经学 神经学
- 行为科学 行为科学
- 临床医学 临床医学
背景情况:
- 肌缩侧面硬化症 (ALS) 和带前性痴呆症 (ALSFTD) 的ALS的特点是运动,认知和行为症状.
- 行为症状对患者,家庭和临床医生构成重大挑战.
- 对这些症状的全面了解对于有效的患者管理至关重要.
研究的目的:
- 对2011年至2024年间发表的研究进行范围审查.
- 介绍ALS和ALSFTD中观察到的各种行为症状.
- 探索这些症状是如何描述和评估的,并识别现有文献中的模式.
主要方法:
- 对科学文献进行了系统的搜索.
- 包括在2011年至2024年间发表的研究.
- 数据被提取并进行主题分析,以分类行为症状和评估方法.
主要成果:
- 该审查从3939篇文章中确定了111项符合条件的研究.
- 行为症状被广泛分为无抑制,冷漠,坚持性/强迫性行为,高口气,失去同情/同情心,精神病症状和洞察力丧失.
- 大多数研究 (78.37%) 使用了经过验证的行为评估,通常包含护理人员的观点.
结论:
- 尽管在ALS/ALSFTD中存在行为症状,但在临床实践中对其进行评估和管理往往是有限的.
- 临床医生应优先评估行为症状,因为它们对预后,治疗参与和家庭痛苦的影响.
- 护理人员报告的措施,特别是采访,对于检测无意识症,缺乏同情心和缺乏同情心是有价值的.
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