脑卒中后早期阻塞性睡眠呼吸暂停的患病率和检测
medRxiv : the preprint server for health sciences
|July 1, 2024
概括
未被诊断的阻塞性睡眠呼吸暂停 (OSA) 在早期中风恢复过程中很常见. 一种简单的查工具BASH可以有效地识别患有OSA风险的患者,从而有可能改善功能恢复结果.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 康复医学 康复医学 康复医学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 显著阻碍了中风后的恢复.
- 早期发现未诊断的OSA对于优化患者的治疗结果至关重要.
- 本研究涉及急性中风阶段OSA的流行和查.
研究的目的:
- 为了确定未诊断的阻塞性睡眠呼吸暂停 (OSA) 在中风恢复的早期阶段患者的患病率.
- 引入和验证一个简单的查工具,BASH工具,用于识别高风险的OSA中风后的个体.
主要方法:
- 一项横截面描述性研究包括123名成人中风患者在中风后大约15天的住院康复中.
- 排除标准包括先前存在的OSA,其他神经疾病,以及无法独立行走.
- 隔夜氧度测量了氧气脱度指数 (ODI);使用ROC曲线分析开发和分析了BASH工具 (BMI>=35,年龄>=50,性别=男性,高血压=是).
主要成果:
- 该研究发现参与者中未被诊断的OSA患病率为22%.
- 接收器操作特征 (ROC) 曲线分析表明,BASH分数为3或更高的有效预测OSA的存在 (AUC=0.746,p<0.001).
- 在OSA检测中,BASH工具的灵敏度为0.778,特异性为0.656.
结论:
- 很大一部分中风幸存者在早期康复阶段未被诊断出阻塞性睡眠呼吸暂停 (OSA).
- 在这个人群中,BASH工具证明了其作为OSA查方法的有效性.
- 早期的OSA检测和中风后的干预可以减轻对功能恢复的负面影响.
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