睡眠和长期COVID:在大量普通人群中,使用3种不同的模型定义,预先存在的睡眠问题和PASC的风险
Stuart F Quan1,2, Matthew D Weaver1,2, Mark É Czeisler3,4,5
1Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
medRxiv : the preprint server for health sciences
|July 1, 2024
概括
失眠,睡眠质量不佳和睡眠时间短暂与SARS-CoV-2感染 (PASC) 后急性后果有关. 改善睡眠可能会降低PASC的风险.
科学领域:
- 睡眠医学 睡眠医学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 众所周知,失眠和睡眠质量差等睡眠障碍与COVID-19感染有关.
- 这些睡眠问题也可能在SARS-CoV-2感染后的长期健康后果的发展中发挥作用.
研究的目的:
- 调查失眠,睡眠质量差,睡眠时间变化与SARS-CoV-2感染的急性后续症状 (PASC) 之间的关联.
主要方法:
- 进行了一项横截面调查,调查了24803名美国成年人.
- 该研究分析了自我报告的睡眠参数与PASC存在之间的关系,使用三个不同的诊断标准.
主要成果:
- PASC与失眠 (aORs 1.30-1.52),睡眠质量差 (aORs 1.77-2.00) 和睡眠时间短 (<6小时,aORs 1.59-1.70) 显著相关.
- 较长的睡眠时间 (≥9小时) 与PASC无关.
- 接种COVID-19增强疫苗减少了PASC的可能性,但没有改变与睡眠相关的危险因素.
结论:
- 失眠,睡眠质量差和睡眠时间短被确定为发展PASC的潜在风险因素.
- 旨在改善睡眠健康的干预措施可能会减轻PASC的风险和发病率.
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