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在采用自然污染的动物料的实验室模型中,吸附剂对菌毒素结合的效率

Adrianna Żybura1, Piotr Jedziniak1

  • 1Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Puławy, Poland.

Journal of veterinary research
|July 1, 2024
PubMed
概括

测试了新的矿物吸附剂,以检测动物料中的结合菌毒素. 当料存在时,结合效率显著下降,这突显了开发有效的真菌毒素结合剂的挑战.

关键词:
用于料添加剂的料添加剂矿物质吸附剂 矿物质吸附剂菌类毒素 (mycotoxin) 是一种有毒的物质.菌毒素结合剂 菌毒素结合剂

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Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
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