由大米爆发真菌Magnaporthe oryzae的septin依赖的入侵生长
Iris Eisermann1, Nicholas J Talbot1
1The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, NR47UH UK.
概括
七是菌植物病原体 (如Magnaporthe oryzae) 感染作物的必需蛋白质. 抑制隔膜聚合为控制谷物疾病的广泛抗真菌化合物提供了一个新的策略.
科学领域:
- 分子生物学分子生物学
- 菌类学 菌类学是指菌类学.
- 植物病理学 植物病理学
背景情况:
- 七GTPases是保存的真核蛋白质,对细胞分裂和发育至关重要.
- 在真菌病原体Magnaporthe oryzae中, septins对于感染结构,如appressoria和transpressoria至关重要.
- 七素功能对于突破植物皮质和宿主组织内的细胞间运动是不可或缺的.
研究的目的:
- 审查了解Magnaporthe oryzae中的隔膜生物学方面的最新进展.
- 探索septins作为新作作物疾病控制战略的目标的潜力.
- 为了突出通过隔膜聚合抑制发现广泛的抗真菌化合物.
主要方法:
- 隔膜聚合的遗传和化学抑制.
- 查破坏隔膜环形成的化合物.
- 实地试验评估对谷物疾病的抗真菌疗效.
主要成果:
- 隔膜聚合的特定抑制在遗传或化学上可以防止植物感染Magnaporthe oryzae.
- 查发现了针对隔膜聚合的广谱抗真菌化合物.
- 这些化合物在实地试验中显示出在预防大米爆发和其他谷物疾病方面的有效性.
结论:
- 七是Magnaporthe oryzae中关键的毒性因子,对于植物感染至关重要.
- 准隔膜聚合是开发新型抗真菌剂的有希望的途径.
- 隔膜聚合抑制剂显示出对主要作物疾病的广泛控制的潜力.
更多相关视频
07:36Visualizing Early Infection Sites of Rice Blast Disease Magnaporthe oryzae on Barley Hordeum vulgare Using a Basic Microscope and a Smartphone
Published on: March 17, 2023
1.6K
09:25Genome-wide Analysis of Histone Modifications Distribution using the Chromatin Immunoprecipitation Sequencing Method in Magnaporthe oryzae
Published on: June 2, 2021
2.8K
相关概念视频
Septins
1.8K
Septins are protein filaments forming the cytoskeleton along with the microtubules, microfilaments, intermediate filaments, and other accessory proteins. In 1971 while studying the cell division cycle in mutant Saccharomyces cerevisiae Harwell et al. first identified the septin-related genes playing a crucial role in yeast cytokinesis. Fluorescence microscopy revealed that these proteins localize at the budding neck as rings. These ring-like proteins were then named Septins by John Pringle, and...
1.8K
Role of Septins
1.7K
Septins are the recently discovered fourth major protein component of the cytoskeleton, along with microfilaments, microtubules, and intermediate filaments. These proteins can associate with other cytoskeletal filaments and carry out varied roles or can be free-floating in the cytoplasm.
Cellular Functions of Septins
Recent studies have revealed the multifaceted roles of septins in various cellular processes such as cytokinesis, ciliogenesis, and neurogenesis. Septins act as scaffolds and...
Cellular Functions of Septins
Recent studies have revealed the multifaceted roles of septins in various cellular processes such as cytokinesis, ciliogenesis, and neurogenesis. Septins act as scaffolds and...
1.7K
