末端板变化和脊肌病理在腰部疼痛中的作用:叙述性综述
Manasa Suryadevara1, Gaurav V Mishra1, Pratapsingh Parihar1
1Radiodiagnosis, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus
|July 1, 2024
概括
退行性磁盘疾病和副脊柱肌肉变化,包括Modik变化,是腰部疼痛的关键因素. 了解这些因素有助于确定子组,以便更好地诊断和治疗慢性背痛.
科学领域:
- 整形外科 整形外科 整形外科
- 放射学 放射学是一门学科.
- 生物化学 生物化学
背景情况:
- 腰椎间盘退化是慢性腰部疼痛的主要原因,往往具有诊断限制.
- 由纤维化和脂肪透的特征的副脊柱肌肉功能障碍与腰部疼痛疾病密切相关.
- 在MRI上观察到的模态变化,代表脊椎末板骨髓变化,与磁盘退化和背部疼痛相关.
研究的目的:
- 编译和综合研究背部疼痛发展背后的生化过程.
- 为了增强对Modic变化,副脊柱肌肉和腰部疼痛之间的关系的理解.
- 确定导致腰部疼痛的关键因素,以改善诊断分组.
主要方法:
- 用谷歌学者和PubMed.Med进行文献综述和研究汇编.
- 关键词包括"模态变化"",末盘变化"",脊柱肌肉"和"腰部疼痛".
- 分析重点关注与腰部疼痛相关的生化途径和结构变化.
主要成果:
- 在腰椎间盘退化,副脊柱肌肉变化 (纤维化,脂肪透) 和腰部疼痛患者的莫迪克变化之间发现了显著的关联.
- 模态变化是磁盘退化的常见指标,在有症状的患者中普遍存在.
- 磁盘,骨髓和肌肉病理之间的相互作用有助于腰部疼痛的发展.
结论:
- 了解莫迪克变化和副脊柱肌肉退化的作用对于诊断和管理腰部疼痛至关重要.
- 根据这些生物标志物识别下腰痛的特定亚组,可以导致更有针对性的治疗.
- 对生化机制的进一步研究是必要的,以充分阐明腰部疼痛的病因.
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