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基于aptamer的纳米医学的计算边界用于精密治疗:全面的审查

Shubham Kumar¹, Anand Mohan¹, Neeta Raj Sharma¹

¹School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab 144001, India.

|July 1, 2024

概括

胺剂是多功能分子工具,为向治疗和诊断而彻底改变纳米医学. 计算方法,包括人工智能和机器学习,增强了aptamer的发展,克服了先进生物医学应用的挑战.

科学领域:

纳米医学是一种纳米医学.
生物技术是生物技术.
计算生物学计算生物学

背景情况:

在纳米医学中,阿普塔默与抗体相比具有优势,包括高选择性和低免疫性.
通过指数式丰富 (SELEX) 的联体的系统进化是体发展的关键过程.
胺剂对于向药物输送,精准医学和诊断至关重要.

研究的目的:

探索纳米医学中aptamers的计算特征和发展.
为了突出阿普坦体对抗体的优势.
讨论AI,ML,物联网和IoMT在aptamer研究中的整合.

主要方法:

对计算型阿普塔默开发流程的审查.
对SELEX方法的分析.
在aptamer选择和优化中探索AI,ML,IoT和IoMT集成.

主要成果:

适合剂在向治疗和诊断方面显示出显著的潜力.
计算工具和人工智能/ML加速了aptamer的发现和改进.
先进技术的整合解决了海发展的挑战.

结论:

亚胺在推进纳米医学的关键作用,为抗体提供了优越的替代品.
计算方法和新兴技术对于释放aptamer潜力至关重要.
需要进一步的研究来解决人工智能驱动的aptamer开发中的挑战和伦理考虑.

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