P2RX7在细胞外囊泡介导的微质和星体细胞的致病分子分泌中发挥着关键作用

Mohammad Abdullah1, Zhi Ruan1, Seiko Ikezu1

  • 1Department of Neuroscience Mayo Clinic Florida Jacksonville Florida USA.

概括

纯能受体P2X7 (P2RX7) 抑制剂GSK1482160减少了微质细胞和星体细胞的细胞外囊泡 (EV) 分泌. 这种依赖P2RX7的机制准神经炎症和传播.

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