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接受母乳或混合养的早产婴儿的肠道微生物群
Sandra Gabriela Sánchez-González1, Bárbara Gabriela Cárdenas-Del-Castillo2, Elvira Garza-González3
1Department of Pediatrics, Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León, Monterrey 64460, Nuevo León, México. sandra_gabriela87@hotmail.com.
World journal of clinical pediatrics
|July 1, 2024
概括
哺乳期早产婴儿的肠道细菌发生变化,Alphaproteobacteria和Betaproteobacteria减少,而Gammaproteobacteria增加. 这项研究分析了出生体重非常低的婴儿的肠道微生物群. 关键词:早产,肠道微生物群,母乳.
科学领域:
- 微生物学 微生物学
- 新生儿科学 新生儿科学
- 儿科 儿科 儿科
背景情况:
- 过早分娩是新生儿死亡的主要原因,经常导致出生体重非常低的婴儿出现并发症.
- 母乳对于早产婴儿至关重要,因为它含有有益的微生物,支持肠道殖民.
- 关键的有益细菌包括乳酸菌和双菌.
研究的目的:
- 为了研究母乳养的早产婴儿的肠道微生物组成.
- 为了分析出生时体重为1500克或更小的婴儿.
主要方法:
- 一项观察性研究包括40名早产新生儿 (怀孕期高达36.6周,出生体重≤1500克).
- 婴儿被分为母乳 (BM) 和混合养 (MF) 组.
- 用便样本的16SrRNA基因测序分析了肠道微生物群.
主要成果:
- 在养组之间没有发现显著的属级差异.
- 母乳养显示了Alphaproteobacteria和Betaproteobacteria的减少,以及Gammaproteobacteria的增加.
- 从最初的样本到最后的样本,物种丰富度下降,不论养类型如何.
结论:
- 哺乳会影响非常低出生体重的早产婴儿的肠道微生物群结构.
- 观察到的变化包括减少的Alphaproteobacteria/Betaproteobacteria和增加的Gammaproteobacteria.
- 这有助于理解这种脆弱人群的肠道微生物群.
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