[减少生育能力的生殖策略:生育能力的保护]
1( 610041) Department of Reproductive Medicine, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
概括
在全球生育率下降的背景下,生育率的保护提供了希望,保护了癌症患者和其他面临生育挑战的人的生殖潜力. 诸如卵细胞,胚胎和卵巢组织冷保存等技术使未来的父母成为可能.
科学领域:
- 生殖医学 生殖医学
- 在瘤学瘤学.
- 遗传学 是一个遗传学.
背景情况:
- 全球生育率正在下降,这给人类的生殖带来了重大挑战.
- 化疗和放射治疗等癌症治疗可以损害生育能力,需要保持生育能力.
- 癌症生存率的进步增加了对生育能力保护策略的需求.
研究的目的:
- 审查当前的生育保存方法及其有效性.
- 突出生育保护在管理医学治疗引起的淋巴毒性的作用.
- 讨论各种生育保存技术的成功率和应用.
主要方法:
- 卵子细胞冷保存
- 胚胎冷保存 胚胎冷保存
- 为女性进行卵巢组织冷保存 (OTC).
- 对于男性来说,冷精子和丸组织冷.
主要成果:
- 活产率 (LBR) 不同: 32%用于IVF-ET的卵子冷保存, 41%用于胚胎移植, 33%用于OTC.
- OTC恢复自然生育能力和内分泌功能,并观察到100%的卵巢功能恢复.
- 结冷保存材料的利用率在2.6%至30.3%之间,取决于方法.
结论:
- 保护生育能力对于因医疗状况或治疗而面临生育能力丧失的个人来说是一个至关重要的方法.
- 对青春期前的女孩来说,OTC是一种至关重要的选择,而对于男孩来说,丸组织的冷保存是实验性的.
- 在应用生育保护来维护患者和后代权利时,道德考虑至关重要.
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