作为COVID-19患者低血风险因素的CT半定量得分:一个横截面研究
Baofeng Wu1,2, Ru Li1,2, Jinxuan Hao1,2
1Department of Endocrinology, First Hospital of Shanxi Medical University, Taiyuan, China.
Frontiers in endocrinology
|July 1, 2024
概括
半定量CT视觉评分可以预测COVID-19患者的低血症,表明更严重的肺病变. 这一分数,加上年龄和其他因素,有助于识别患有低血风险的患者.
科学领域:
- 放射学 放射学是一门学科.
- 传染性疾病 传染性疾病
- 内分泌学 在内分泌学.
背景情况:
- 胸部计算机断层扫描 (CT) 对于评估COVID-19肺炎的严重程度至关重要.
- 肺炎,特别是COVID-19肺炎,经常与低血症有关.
- 了解COVID-19中低血的预测因素对于临床管理至关重要.
研究的目的:
- 评估COVID-19患者中低血症半定量CT视觉评分的预测能力.
- 在COVID-19的背景下识别与低血症相关的危险因素.
- 为了探索SARS-CoV-2感染,甲状腺功能和低血症之间的关系.
主要方法:
- 一项涉及343名RT-PCR确诊COVID-19患者的横截面研究.
- 放射科医生对肺部病变进行半定量CT视觉评分.
- 对低血风险因素的分析,包括实验室测试和甲状腺功能.
主要成果:
- 低血症患者的肺病变总重度评分 (TSS) 更高 (3.5对3.0,P=0.001).
- 多变量分析确定了年龄,吐,中性粒细胞,血小板数和CT TSS作为低血的危险因素.
- 低血症患者的自由三甲状腺氨酸 (3.1比3.7,P=0.001) 和甲状腺刺激激素水平 (1.4比2.2,P=0.038) 较低.
结论:
- 半定量CT视觉评分是COVID-19患者中低血症的重要危险因素.
- COVID-19 感染会影响甲状腺功能,甲状腺血量下降与甲状腺激素水平变化有关.
- 在感染SARS-CoV-2的个体中,血清和自由三甲状腺素之间存在微弱的正相关性.
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