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Updated: Jun 22, 2025

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells
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在脏前代细胞中删除NuRD成分Mta2会导致发育编程的FSGS

Jeannine Basta, Lynn Robbins, Lisa Stout

    bioRxiv : the preprint server for biology
    |July 1, 2024
    PubMed
    概括

    出生时脏数量低会增加慢性脏病 (CKD) 的风险. 通过破坏线粒体新陈代谢和脂质处理,在小鼠中删除Mta2导致脏疾病,突出显示了与人类脏疾病的联系.

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