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Updated: Jun 20, 2026

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors
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电脑性GABAergic神经元类型的转录和空间组织

Cindy T J van Velthoven1, Yuan Gao1, Michael Kunst1

  • 1Allen Institute for Brain Science, Seattle, WA, USA.

bioRxiv : the preprint server for biology
|July 1, 2024
PubMed
概括

这项研究绘制了老鼠大脑中GABAergic神经元的复杂世界,揭示了它们的不同类型,起源和迁移模式. 这种全面的分类学为了解大脑功能和疾病提供了至关重要的参考.

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Ligand-Gated Ion Channel Receptor: Gating Mechanism01:30

Ligand-Gated Ion Channel Receptor: Gating Mechanism

Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...