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在氧化应激过程中,局部的K63泛素信号由VCP/p97调节

Austin O Maduka1, Sandhya Manohar2, Matthew W Foster3

  • 1Department of Biology, Duke University, Durham, NC, 27708, USA.

bioRxiv : the preprint server for biology
|July 1, 2024
PubMed
概括

氧化应激会导致与K63结合的乌比奎链在非细胞质区块中积聚. 这种无处不在的信号传递,与VCP和NPLOC4一起,对于细胞应激反应和蛋白质处理至关重要.

关键词:
K63 无处不在的存在这是一个VCPVCP.人类细胞是人类细胞.氧化应激是一种氧化应激.亚细胞局部化的局部化

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