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结肠直肠癌切除后的早期随访结肠镜检测出显著的病理
Ben P Finlay1,2, Erin L Symonds3,4, Mahadya Raman2
1Colorectal Surgery Unit, Division of Surgery and Perioperative Medicine, Flinders Medical Centre, Adelaide, South Australia, Australia.
结肠直肠癌切除后及时进行结肠镜检查对于检测晚期瘤至关重要. 在手术后的最初几年,避免在监测结肠镜之间长时间间隔,以改善患者的治疗结果.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 手术瘤学手术瘤学
背景情况:
- 结肠镜检查对于结肠直肠癌 (CRC) 切除后的监测至关重要.
- 目前的监测间隔缺乏可靠的证据,导致全球指导方针的变化.
研究的目的:
- 评估CRC切除后监测结肠镜检查的最佳时间和结果.
- 评估后续结肠镜检查中晚期瘤的检测率.
主要方法:
- 使用前性收集的数据进行回顾性队列研究.
- 包括接受监视后CRC切除的成年患者,但不包括特殊情况.
- 对高级瘤的最多三次随访结肠镜检查的经过审计的结果.
主要成果:
- 在980名患者中,第一次结肠镜检查的中位数为12.4个月,检测到2.7%的CRC和13.2%的晚期腺瘤.
- 诸如老年和疾病晚期等因素与瘤检测相关.
- 随后的结肠镜检测显示了持续的检测率,而先前的腺瘤预测了未来的发现. 在监测期间,4.4%的人患上了CRC.
结论:
- 在CRC切除后迅速进行结肠镜监测对于识别晚期瘤至关重要.
- 应尽量减少早期监测结肠镜检查之间的长时间间隔,以提高检测和患者管理.
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