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Updated: Jun 22, 2025

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery
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在成功的小分子药物发现中出现"自然选择"

A Lina Heinzke1, Axel Pahl2, Barbara Zdrazil1

  • 1European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton CB10 1SD, Cambridgeshire, U.K.

Journal of medicinal chemistry
|July 1, 2024
PubMed
概括

药物发现表明"自然选择",因为合成化合物模仿自然. 伪天然产品 (PNPs) 在临床药物中越来越常见,这表明大自然的设计原则是成功开发药物的关键.

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