常规心电图查和心血管疾病事件在成年人
Ryuichiro Yagi1,2, Yuichiro Mori3, Shinichi Goto1,4
1Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
JAMA internal medicine
|July 1, 2024
概括
工作成年人的休息心电图 (ECG) 异常与较高的死亡风险和心血管疾病 (CVD) 事件有关. 即使是微小的心电图变化也表明风险增加,这表明早期心血管疾病预防策略的潜力.
科学领域:
- 心脏病学 心脏病学
- 预防医学 预防医学
- 公共卫生 公共卫生
背景情况:
- 静止心电图 (ECG) 是日本常用的心血管疾病 (CVD) 查工具.
- 关于心电图在现实临床环境中的预后意义的证据有限.
研究的目的:
- 调查在劳动年龄人口中ECG异常和心血管疾病结果之间的关联.
- 评估基线心电图发现对未来心血管事件和死亡率的预后价值.
主要方法:
- 一项全国性的队列研究利用了来自日本健康保险协会数据库的数据 (3000万工作人员).
- 包括3,698,429名年龄在35-65岁之间的个人,基线心电图状态分类 (正常,轻微,重大异常).
- 分析了2015年4月至2022年3月的随访数据,以分析死亡和心血管疾病住院的复合结果.
主要成果:
- 基线心电图异常独立地与死亡风险增加和心血管疾病入院有关.
- 与正常心电图相比,患有严重心电图异常的个体几乎有两倍的风险 (aHR,1.96).
- 轻微的心电图异常的存在和数量也预测了发展新的主要心电图异常的发病率增加.
结论:
- 休息时的心电图异常,包括轻微的异常,是工作成年人心血管不良结果的重要预测因素.
- 这些发现支持进一步调查常规心电图查,以早期预防心血管疾病,并优化后续策略.
- 心电图异常的预后价值在心血管风险评估和管理中需要考虑.
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