末端器官免疫细胞的差异变化和对盐敏感高血压的炎症:增加M2巨细胞的影响

Shobana Navaneethabalakrishnan1, Bethany L Goodlett1, Hannah L Smith1

  • 1Department of Medical Physiology, Texas A&M University College of Medicine, Bryan, TX, U.S.A.

概括

这项研究表明,AVE0991 (AVE) 治疗通过促进M2巨细胞极化和改善器官功能来降低盐敏感高血压 (SSHTN) 模型中的高血压和炎症.

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Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
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