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Updated: Jun 22, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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不对称的有机催化1,3-二极循环添加亚甲化物与β替代的循环子

Han Zhong1, Xiao-Yi Zhang1, Yong-Mou Yao1

  • 1The Fifth Affiliated Hospital and Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Xinzao, Panyu District, Guangzhou 511436, China.

The Journal of organic chemistry
|July 1, 2024
PubMed
概括

这项研究引入了一种新的方法,用于控制1,3-双极循环添加反应中的立体化学. 它可以合成具有高反选择性和异选择性复杂的合性他衍生物.

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