评估患者报告的特殊疾病状态的坚持和结果:双站点倡议
E Danielle Bryan1, Chelsea P Renfro1, Rebekah H Anguiano2
1Vanderbilt Specialty Pharmacy, Vanderbilt University Medical Center, Nashville, TN.
Journal of managed care & specialty pharmacy
|July 1, 2024
概括
患者报告的结果显示,在多发性硬化症 (MS) 和类风湿病中,专用药物的高有效性和坚持. 耐受性问题和感知效率较低可能会增加遗漏剂量,这表明需要加强患者监测.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 患者报告的结果
- 专业药房 专业药房 专业药房
背景情况:
- 患者报告的结果 (PROs) 对于评估患者对多发性硬化症 (MS) 和类风湿病的专用药物的反应至关重要.
- 了解PRO和患者特征之间的关联可以增强以患者为中心的治疗监测.
研究的目的:
- 检查患者特征和PRO之间的关联,包括药物坚持,药物耐受性,感知有效性和医疗保健资源利用率 (HCRU).
- 为了分析这些关联,患者在两个医疗保健系统专业药房处方特殊药物.
主要方法:
- 来自两个专业药房的每月药物评估的回顾性审查 (2019年10月-2022年3月).
- 包括接受至少三次风湿学或多发性硬化症专用药物的患者.
- 使用混合效应后勤回归来测试PRO和患者特征之间的关联.
主要成果:
- 来自3,677名患者的61,000多项评估显示,高感知效率 (93.9%) 和坚持.
- 1.5%的患者报告了耐受性问题,但与错过剂量增加2.5倍的可能性有关.
- 与好/优秀评级相比,公平的感知有效性将遗漏剂量的几率提高了61%.
结论:
- 用于MS和类风湿病的特殊药物治疗的患者报告高效率和坚持.
- 耐受性问题和较低的感知有效性与不遵守相关,表明需要针对性监测患者.
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