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一种多箱稀释方法用于评估TCR测序数据中的α多样性

Mo Li1, Xing Hua2, Shuai Li3

  • 1Department of Mathematics, University of Louisiana at Lafayette, Lafayette, LA, 70504, United States.

Bioinformatics (Oxford, England)
|July 1, 2024
PubMed
概括

一种新的多箱稀释方法通过解决图书馆大小差异来准确估计T细胞受体 (TCR) 多样性. 这种方法改善了整体稀释,为免疫力学研究提供了更好的控制和统计能力.

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
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