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Updated: Jun 22, 2025

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
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Published on: September 18, 2013

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基尼尔尼古丁胺胺在耐药性急性髓性白血病中表现出抗白血病活性

Baskar Ramdas1, Neetu Dayal2, Ruchi Pandey1

  • 1Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.

The Journal of clinical investigation
|July 1, 2024
PubMed
概括

基于尼古丁胺的新型FLT3抑制剂HSN608和HSN748对FLT3突变的急性髓性白血病 (AML) 显示出强大的疗效. 这些化合物对抗耐药突变有效,并在体内表现优于吉尔特里尼布.

关键词:
血液学 血液学 血液学造血干细胞 造血干细胞 造血干细胞干细胞是一种干细胞.

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