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Updated: Jun 30, 2026

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怀孕期间的mRNA COVID-19 疫苗接种与新生儿不良结果的增加无关

Robert P Kauffman¹

¹Texas Tech University School of Medicine, Amarillo, Texas, USA (R.P.K.).

Annals of internal medicine

|July 1, 2024

概括

在怀孕期间接种COVID-19疫苗并没有增加新生儿的风险. 这项研究发现,接种疫苗和未接种疫苗的母亲之间新生儿结局没有显著差异,支持怀孕期间疫苗的安全性.

科学领域:

产科和妇科产科和妇科
新生儿健康新生儿健康
传染病流行病学传染病流行病学

背景情况:

怀孕期间接种2019年新冠肺炎疾病 (COVID-19) 疫苗的安全性是一个关键的公共卫生问题.
了解母体COVID-19疫苗接种对新生儿结果的影响,对于临床指导和家长决策至关重要.

研究的目的:

评估孕妇在怀孕期间接种COVID-19疫苗和各种新生儿结果之间的关联.
为了比较接受COVID-19疫苗接种的母亲所产生的婴儿与未接种疫苗的母亲所产生的新生儿不良事件的发生率.

主要方法:

一个回顾性队列研究,利用大规模的健康数据.
包括接受COVID-19疫苗接种的孕妇和一个可比的未接种疫苗的组.
对新生儿结局的分析,包括早产,对于妊娠年龄来说小,先天性异常和新生儿单位入院.

主要成果:

与未接种疫苗的母亲相比,在接种疫苗的母亲的婴儿中没有观察到过早分娩风险的统计学上显著增加.
妊娠年龄的婴儿和先天性异常的发病率在两组之间相似.
接受新生儿病房的婴儿在接受孕产妇COVID-19疫苗接种的婴儿和未接种疫苗的婴儿之间没有显著差异.

结论:

孕妇在怀孕期间接种COVID-19疫苗与新生儿不良结果无关.
这些发现支持COVID-19疫苗对孕妇及其新生儿的安全性.
这些证据可以为临床建议和关于怀孕期间接种疫苗的公共卫生信息提供信息.

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