2型糖尿病患者的嗅觉功能障碍.
A Cardella1, A Ferrulli2, S Vujosevic3
1Department of Otorhinolaryngology, IRCCS Multimedica, Milan, Italy; Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Rhinology
|July 1, 2024
概括
糖尿病并发症在2型糖尿病患者中显著增加嗅觉功能障碍 (OD). 低血糖控制,LDL,年龄和大血管问题是T2DM中OD的关键预测因素.
科学领域:
- 内分泌学 在内分泌学.
- 神经学 神经学
- 眼科医生 眼科 眼科
背景情况:
- 嗅觉功能障碍 (OD) 在2型糖尿病 (T2DM) 中越来越多地被认可.
- OD和糖尿病并发症之间的关系需要进一步调查.
研究的目的:
- 为了确定T2DM患者OD的患病率.
- 分析OD与糖尿病并发症存在的关联.
主要方法:
- 130名T2DM患者和100名对照人群使用扩展嗅觉测试 (TDI) 和意大利简要嗅觉障碍问卷 (Brief-IT-QOD) 进行了评估.
- 二型糖尿病患者根据并发症的存在或不存在被分为不同的群体.
- 机器学习算法被用来识别OD的预测因素.
主要成果:
- 与没有 (43.3%) 和对照 (30%) 患者相比,T2DM并发症患者 (71.4%) 的OD患病率显著更高.
- 在T2DM中OD的关键预测因素包括LDL,糖化血红蛋白,大血管并发症和年龄.
- 为预测T2DM患者的OD风险,开发了一个名图.
结论:
- 糖尿病并发症与T2DM中OD的更高患病率有关.
- 血糖控制不良,LDL升高,晚年和大血管并发症是导致T2DM中OD的重要因素.
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