左心室 - 大动脉角的变化与高性心肌病症中阻塞的发展有关
Defne Gunes Ergi1, Hartzell V Schaff1, Steven R Ommen2
1Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minn.
The Journal of thoracic and cardiovascular surgery
|July 1, 2024
概括
患有左心室外流通道阻塞的高性心肌病患者表现出心室角和高的增加. 密特拉变化与阻塞进展无关.
科学领域:
- 心脏病学 心脏病学
- 心脏成像 - - 心脏成像
- 心血管疾病 心血管疾病
背景情况:
- 增高性心肌病变 (HCM) 是一种遗传性心肌疾病.
- 左心室 (LV) 外流通道阻塞可以在HCM患者中发展.
- 了解形态变化对于管理HCM进展至关重要.
研究的目的:
- 在患有LV外流通道阻塞的HCM患者中表征心室形态变化.
- 为了将这些变化与保持非阻塞性HCM患者进行比较.
主要方法:
- 对接受隔膜肌切除术的HCM患者的回顾性审查 (2012年5月-2023年6月).
- 患有阻塞的患者与保持非阻塞的患者之间的比较.
- 根据性别,年龄和初始隔膜壁厚度进行匹配对分析.
- 对心声回声图数据的分析,包括5个角度测量.
主要成果:
- 与非阻塞患者相比,阻塞患者的LV质量增加更大.
- 在阻塞组的5项测量中,在4项测量中观察到大动脉角的显著增加.
- 在这两组中,隔膜壁厚度都增加了,但增加的幅度没有差异.
- 高血压在患有阻塞的患者中更为普遍.
结论:
- 在HCM中,LV外流通道阻塞的发展与渐进的LV角和增加的LV缩 (LV质量) 有关.
- mitra 的说明书形态和合长度没有显著变化,也与阻塞进展无关.
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